Labdane Aldehyde Diterpenoids from Curcuma mangga Rhizome
Muhammad Widyo Wartono, Qurotul Aini, Venty Suryanti, Maulidan Firdaus, Fajar Rakhman Wibowo, Soerya Dewi Marliyana, Triana Kusumaningsih, Desi Suci Handayani
J. Pure App. Chem. Res. Vol 12, No 3 (2023), pp. 157-165
Submitted: April 20, 2022     Accepted: December 28, 2023     Published: December 28, 2023
DOI: http://dx.doi.org/10.21776/ub.jpacr.2023.012.03.694

Abstract


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Curcuma mangga val. (Zingiberaceae) is one of the plants that used as traditional medicine by Indonesian. Several studies have been reported on the content of compounds of C. mangga, but it is not yet known which compounds have medicinal properties. In this study, two labdane diterpenes were isolated from the extract of rhizome of C. mangga. Determination of the structure conducted by NMR (1H, 13C, HSQC and HMBC) that obtained two compounds, calcaratarin A (1) and labda-8(17),12-diene-15,16-dial (2). Both compounds have an aldehyde functional group. However, both compounds did not show antibacterial activity on Escherichia coli.


Keywords : Curcuma mangga; labdane, diterpene, antibacterial, Zingiberaceae
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