Synthesis and Characterization of Fe3O4 Nanoparticles Modified with Polyethylene Glycol as Antibacterial Material
Poedji Loekitowati Hariani, Desnelli Desnelli, Fatma Fatma, Rizki Indah Putri, Salni Salni
J. Pure App. Chem. Res. Vol 7, No 2 (2018), pp. 122-129
Submitted: November 24, 2017     Accepted: February 23, 2018     Published: May 07, 2018


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The iron oxide (Fe3O4) nanoparticles modified with polyethylene glycol (PEG) was synthesized by co-precipitation methods using ferric and ferrous ions as the precursors. Further, the antibacterial activity was performed against gram-positive and gram-negative bacteria. The Fe3O4-PEG was characterized using X-Ray Diffraction (XRD), Fourier Transform Infra Red (FTIR), Scanning Electron Microscopy (SEM) with energy dispersive X-Ray analysis (EDAX) and Vibrating Sample Magnetometer (VSM). The particle size of Fe3O4-PEG calculated using XRD is 46.2 nm. The study confirmed that Fe3O4-PEG is superparamagnetic and has a saturation magnetization of 56.43 emu/g. The prepared Fe3O4-PEG gives the effect of both gram-positive and gram-negative pathogenic bacterial strains hence this material has potential utilization in the field of pharmaceutical and biomedical in the future.


Keywords : Fe3O4, nanoparticle, PEG, antibacterial activity
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