A Flavonoid Glycoside Compound Isolated from Macaranga gigantifolia Merr Leaves
Gian Primahana, Akhmad Darmawan
J. Pure App. Chem. Res. Vol 6, No 1 (2017), pp. 22-26
Submitted: August 03, 2016     Accepted: January 04, 2017     Published: January 09, 2017
DOI: http://dx.doi.org/10.21776/ub.jpacr.2017.006.01.298

Abstract


Cover Image

Apigenin-8-C-glycoside (1), a flavonoid glycoside compound has been isolated from the leaves of Macaranga gigantifolia Merr. Isolation and purification conducted by chromatography methods and chemical structure characterization carried out by spectroscopic methods. Cytotoxicity of Apigenin-8-C-glycoside has been tested against Murine leukemia P-388 cell lines and has moderate activity with IC50 values 55.4 μg/mL.


Keywords : Apigenin-8-C-glycoside, Macaranga gigantifolia Merr., Murine leukemia P-388 cell lines.
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