Effect of beta-Carotene from Yellow Ambon Banana Peel on Rat Serum Retinol Level
Suparmi Suparmi, Harka Prasetya, Martanto Martosupono, Lasmono Tri Sunaryanto
J. Pure App. Chem. Res. Vol 3, No 2 (2014), pp. 83-87
Submitted: February 16, 2014     Accepted: June 02, 2014     Published: August 21, 2014


Vitamin A Deficiency (VAD) is associated with significant morbidity and mortality from common childhood infections and is the world’s leading preventable cause of childhood blindness. Studies showed that carotenoid is one of the promissed vitamin A source. However the studies  on  carotenoid from yellow  banana peel and its potential as a natural source of vitamin A has not been widely reported. This study was conducted to measure the blood serum retinol levels of rats after administration of β-carotene from yellow ambon banana peel. This was an experimental study with post test only control group design, with sample size of 18 rats with age 1 month, devided into 3 groups. β-carotene dose administered based on the dose of red capsules vitamin A are (200,000 doses SI) for toddlers aged 12-59 months. Serum retinol levels were measured using a spectrophotometer according metide. This present study showed that the blood serum  level in group treated with  of β - carotene from yellow ambon banana peel (28.35 ± 1.61 mg/ dL ), was significantly different (p < 0.05) from that of   control group ( 22.08 ± 1.35 mg /dL ). β-carotene from yellow ambon banana peel are potential as provitamin A.

Keywords : β-carotene, retinol, peel, yellow ambon banana, VAD
Full Text: PDF


. WHO. Serum retinol concentrations for determining the prevalence of vitamin A deficiency in populations. Vitamin and Mineral Nutrition Information System. Geneva, World Health Organization, 2011 (WHO/NMH/NHD/MNM/11.3). http://www.who.int/vmnis/indicators/ retinol.pdf, Accessed 10 January 2014.

. Departemen Kesehatan Republik Indonesia, Deteksi Dini dan Tatalaksana kasus Xeropthamia, 2013, Accessed from http://www.depkes.go.id/index.php?vw= 2&id=A-342. Date 12 February 2014.

. Drupadi Dillon, Min K. Htet, Faraja P. Chiwile, Med. J. Indonesia, 2010, 19, 258-63.

. Astawan, M., Vitamin A Bukan Hanya untuk Mata. http://cybermed.cbn.net.id/cbprtl/cybermed/detail.aspx?x=Nutrition&y=cybermed|0|0|6|558. Date accessed 6 November 2012.

. Anwar. F. Minyak Sawit Bikin Jantung Sehat Dan Awet Muda. Accessed from http://www.kompas.com/kesehatan/news/senior/gizi/0207/25/gizi.htm. Date accessed 12 February 2014.

. Kompas, Khasiat Kulit Pisang untuk Depresi dan Kesehatan Retina. www.kompas.com. Date accessed 5 March 2009.

. Suparmi and Prasetya. H. Isolation and Identification of Carotenoid Pigments of Yellow Ambon Banana Peel (Musa paradisiaca sapientum L.). Prosiding International Conference on Natural Sciences 2012 (ICONS 2011), 83-91

. Suparmi dan Harka Prasetya, Sains Medika, 2012, 4 (1), 78-88.

. Gross. J., Pigment in Vegetables. Chlorophyll and Carotenoids. 1991. Van Nostrand Reinhold, New York.

. Saskia de Pee and O. Dary, J. Nutr., 2002, 132, 2895S–2901S

. Britton. G., Liaaen-Jensen. S., and Pfander. H. Carotenoids Volume IA: Isolation and Analysis. 1995, Birkhauser Verlag, Berlin, p47.

. Permaesih. D., Gizi Indonesia, 2008, 31 (2), 92-97.

. Fiona M. Herr, Sarah A. Wardlaw, Bharati Kakkad, Alberta Albrecht, Timothy C. Quick, and David E. Ong. J. Lipid Res., 1993, 34, 1545-1554.

. Super Nutrition, The Truth About Vitamin A (Retinol) & Beta-Carotene. 1995. Number 6d, March, 2009.


  • There are currently no refbacks.